Picayune Hotel Reservations

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Photo of The Henry Smith House hotel in Picayune The Henry Smith House
99 Henry Smith Road
Picayune, Mississippi


Guestrooms. 
This 19th century Mississippi bed and breakfast offers a seasonal outdoor pool and full hot breakfast. Free Wi-Fi is provided. More

from $150.00* USD

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Photo of Holiday Inn Express Hotel & Suites Picayune hotel in Picayune Holiday Inn Express Hotel & Suites Picayune
1001 Dauphin Street
Picayune, Mississippi


Guestrooms. 
Guest rooms at this Picayune, Mississippi hotel include 32-inch flat-screen cable TVs. An indoor pool and a gym are available More

from $88.99* USD

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Photo of Heritage Inn hotel in Picayune Heritage Inn
1122 Memorial Boulevard
Picayune, Mississippi


Guestrooms. 
Located off Interstate 59, this Picayune motel features a free continental breakfast. Free Wi-Fi is provided in every room. The More

from $64.99* USD

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Photo of Econo Lodge Picayune hotel in Picayune Econo Lodge Picayune
550 South Lofton Drive
Picayune, Mississippi


Guestrooms. 
The Econo Lodge hotel is located within one hour of New Orleans and many Gulfport casinos. This hotel is convenient More

from $59.95* USD

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Photo of Super 8 Picayune hotel in Picayune Super 8 Picayune
999 Cooper Road
Picayune, Mississippi


Guestrooms. 
This motel is located in Picayune, Mississippi and offers free WiFi access and a complimentary breakfast. Highland Community Hospital is More

from $42.49* USD

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Photo of Days Inn Picayune hotel in Picayune Days Inn Picayune
450 South Loftin Avenue
Picayune, Mississippi


Guestrooms. 
Free WiFi access and an outdoor pool are featured at Days Inn Picayune. This motel is located just off Interstate More

from $59.46* USD

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